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Once Dr Robert Tepper discovered his passion for medical research, he followed it throughout his career. As a Princeton college student with an interest in German, Tepper's first research job was working summers in a leukemia laboratory at Mt Sinai. Through strong mentorship there and at Princeton, Harvard Medical School (HMS), and Massachusetts General Hospital (MGH), Tepper became a successful NIH-funded cancer and immunology researcher. When given an opportunity to join Millennium Pharmaceuticals, Tepper debated if he should leave the world of academic medicine, and ultimately decided that Millennium's emphasis on collaboration was an ideal fit. Tepper worked at Millennium for several years before starting Third Rock Ventures with previous valued coworkers. Third Rock allowed him to remain focused on developing new and exciting science that had the promise to improve medicine and help those around him. Tepper's ability to identify and follow his passion led him to academic medicine, industry, and venture capital. He found strong mentorship, built a network, and worked with valued colleagues in a collaborative environment. He took risks along the way, which altered his career path, but even he would tell you that the path doesn't matter, it's all about following your passion.