Product details

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Published by: Stanford Business School
Originally published in: 2004
Version: 15 February 2005
Length: 23 pages
Data source: Field research

Abstract

The case details the efforts of VaxGen and its President, Don Francis, to obtain approval to conduct Phase III clinical trials in Thailand for AIDSVAX, an experimental vaccine designed to protect against human immunodeficiency virus (HIV), the virus that causes AIDS. Francis must grapple with a host of ethical questions, from how certain he needs to be of the effectiveness of AIDSVAX to warrant the involvement of thousands of subjects in clinical trials, to what type of compensation or treatment, if any, to offer to volunteer subjects in developing countries where the standard for AIDS treatment is much lower than in the United States.

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Abstract

The case details the efforts of VaxGen and its President, Don Francis, to obtain approval to conduct Phase III clinical trials in Thailand for AIDSVAX, an experimental vaccine designed to protect against human immunodeficiency virus (HIV), the virus that causes AIDS. Francis must grapple with a host of ethical questions, from how certain he needs to be of the effectiveness of AIDSVAX to warrant the involvement of thousands of subjects in clinical trials, to what type of compensation or treatment, if any, to offer to volunteer subjects in developing countries where the standard for AIDS treatment is much lower than in the United States.

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