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Established in 1853, Aetna Inc (Aetna) had evolved into the third largest healthcare insurance company in the US providing healthcare benefits to about forty-four million people. Aetna's growth in the US healthcare sector was led by Mark Bertolini (Bertolini), who focused on people’s health improvement at an affordable cost. Aetna’s business was spread over North America, Asia, Europe and the Middle East. The US healthcare sector was revolutionised by the Affordable Care Act (2010), and the health insurance companies proactively moved to formulate business models in keeping with the provisions of the new Act. Aetna prepared itself to shift from an insurance carrier to a health solutions provider. It strategically planned to reduce per capita cost and improved delivery as well as the quality of health care. The company also progressed through various mergers and acquisitions in the US healthcare sector which was undergoing a phase of consolidation. Bertolini at the helm of Aetna took forward the company through his unique leadership. Faced with serious personal healthcare issues, Bertolini turned successfully to alternative options of recovery through programs related to yoga, meditation and mindfulness. Further, this approach facilitated creativity, stress reduction, productivity and employee engagement at Aetna. He restructured the company's culture and introduced free yoga, meditation classes while increasing the salaries of the lowest paid employees. As the US healthcare sector was being reinvented, would Aetna prosper under the dynamic leadership of Bertolini in the challenging market environment?